KS100

Overview

KS100 is a potent ALDH inhibitor with IC 50 s of 230, 1542, 193 nM for ALDH1A1, ALDH2 , and ALDH3A1, respectively. KS100 shows antiproliferative and anticancer effects with low low toxic. KS100 significantly increases ROS activity, lipid peroxidation and toxic aldehyde accumulation. KS10600 induces apoptosis and cell cycle arrest at the G2/M phase.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Aldehyde Dehydrogenase (ALDH) | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-146682
• CAS No.: 2408477-54-1
• Molecular Formula: C17H14Br3N3O2S
• Molecular Weight: 564.09
• Purity: 99.61%
• Storage: 4°C, sealed storage, away from moisture * The compound is unstable in solutions, freshly prepared is recommended.
• Availability: In-stock

Source

Original product source