IHMT-TRK-284

Overview

IHMT-TRK-284 (Compound 34) is a potent, orally active type II TRK kinase inhibitor with IC 50 values of 10.5, 0.7, and 2.6 nM to TRKA , B , and C respectively. IHMT-TRK-284 displays great selectivity profile in the kinome and good in vivo antitumor efficacies.

Application

Products | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > c-Fms | Products > Signaling Pathways > PDGFR | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > c-Kit

Product Information

• Catalog No.: HY-146697
• CAS No.: 2416844-79-4
• Molecular Formula: C25H27N7OS
• Molecular Weight: 473.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source