HDAC-IN-37

Overview

HDAC-IN-37 is a potent HDAC inhibitor with IC 50 s of 0.0551 μM, 1.24 μM, 0.948 μM and 34.2 μM for HDAC1 , HDAC3 , HDAC8 and HDAC6 , respectively. HDAC-IN-37 induces histone acetylation in a slow-off manner. HDAC-IN-37 prevents cell transition from G1 phase to S phase and induces early cell apoptosis .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-146750
• CAS No.: 2766466-56-0
• Molecular Formula: C23H24ClN7O
• Molecular Weight: 449.94
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source