hA2A/hCA XII modulator 1

Overview

hA2A/hCA XII modulator 1 (compound 14), a triazolopirazine, is a potent hA 2A adenosine receptor (hA 2A AR) antagonist with K i s of 6.4 nM, 4.819 μM, >30 μM for hA 2A AR, hA 1 AR, hA 3 AR, respectively. hA2A/hCA XII modulator 1 is a potent human carbonic anhydrase XII (hCA XII) inhibitor with K i s of 6.2 nM, 46 nM, 466 nM, 8.351 μM for hCA XII, hCA II, hCA IX and hCA I, respectively. hA2A/hCA XII modulator 1 has the potential for cancer research.

Application

Products | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Adenosine Receptor | Products > Signaling Pathways > Carbonic Anhydrase

Product Information

• Catalog No.: HY-146979
• CAS No.: 2548963-55-7
• Molecular Formula: C24H19N7O4S
• Molecular Weight: 501.52
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source