GSK621

Overview

GSK621 is a specific AMPK activator, with IC 50 values of 13-30 μM for AML cells. GSK621 induces autophagy and apoptosis . GSK621 induces eiF2α phosphorylation-a hallmark of UPR activation.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-100548
• CAS No.: 1346607-05-3
• Molecular Formula: C26H20ClN3O5
• Molecular Weight: 489.91
• Purity: 98.03%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: 1.25 mg/mL (2.55 mM); Suspended solution; Need ultrasonic
• Availability: In-stock

Source

Original product source