CCR4 antagonist 3

Overview

CCR4 antagonist 3 is a potent chemokine receptor 4 ( CCR4 ) antagonist with an IC 50 value of 1.7 μM for [ 125 I]TARC (thymus and activation regulated chemokine). CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine (MDC) to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC (IC50 = 6.4 μM).

Application

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Product Information

• Catalog No.: HY-147385
• CAS No.: 1957-01-3
• Molecular Formula: C14H12N2S
• Molecular Weight: 240.32
• Purity: 99.94%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source