ARUK3001185

Overview

ARUK3001185 is a potent, selective, orally active and brain-penetrant inhibitor of Notum ( IC 50 = 6.7 nM). ARUK3001185 can restore Wnt signaling in the presence of Notum in vitro. ARUK3001185 is selective against serine hydrolases , kinases, and drug targets. ARUK3001185 can be used to research the role of Notum plays in diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Depression | Products > Disease Areas > Obesity | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > Wnt

Product Information

• Catalog No.: HY-147519
• CAS No.: 2411969-39-4
• Molecular Formula: C9H4Cl2F3N3
• Molecular Weight: 282.05
• Purity: 99.28%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source