hCAIX-IN-8

Overview

hCAIX-IN-8 (compound 7i) is a potent and selective hCAIX inhibitor with IC 50 s of 1.99, 0.024, 1.10 μM for CAII, CAIX, CAVA respectively. hCAIX-IN-8 shows anti-proliferation activity with low toxicity. hCAIX-IN-8 decreases the epithelial to mesenchymal transitions and induces apoptosis . hCAIX-IN-8 inhibits cell migration and colonization potential.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carbonic Anhydrase

Product Information

• Catalog No.: HY-147722
• CAS No.: 2414633-40-0
• Molecular Formula: C19H16N4O6
• Molecular Weight: 396.35
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source