MMP2-IN-2 (compound 42) is a potent and selective MMP-2 ( matrix metalloproteinases ) inhibitor, with an IC 50 of 4.2 μM. MMP2-IN-2 also shows inhibitory activity against MMP-13 , MMP-9 and MMP-8 , with IC 50 values of 12, 23.3, and 25 μM, respectively.
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