hCAIX-IN-11

Overview

hCAIX-IN-11 (Compound 5d) is a selective carbonic anhydrase IX and XII inhibitor with K i s of 32.7 and 623.5 nM for hCA IX and hCA XII, respectively. hCA IX and hCA XII are transmembrane isoforms which have been characterized as biomarkers for several types of tumors. The hCA XII assists in maintenance of acid-base homoeostasis in normal as well as tumor cells.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Carbonic Anhydrase

Product Information

• Catalog No.: HY-147828
• CAS No.: 2497504-81-9
• Molecular Formula: C21H15ClN4O3
• Molecular Weight: 406.82
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source