EGFR-IN-61

Overview

EGFR-IN-61 (compound 22a) is a potent EGFR kinase inhibitor, with IC 50 values of 42 nM (L858R/T790 M), 137 nM (L858R/T790 M/C797S), and 743 nM (WT), respectively. EGFR-IN-61 shows antiproliferative activity against A549 and H1975 cell lines, with IC 50 values of 2.14 and 1.82 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-147860
• CAS No.: 2890261-81-9
• Molecular Formula: C33H37ClN8O3
• Molecular Weight: 629.15
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source