Tubulin inhibitor 29 (compound 3c) is a potent tubulin inhibitor with an IC 50 value of 1.2 µM. Tubulin inhibitor 29 shows antiproliferative effects with an IC 50 value of 7.5 µM for MCF-7 cells. Tubulin inhibitor 29 inhibits tubulin assembly and bounds in the colchicine site.
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