I-287

Overview

I-287 is a orally active selective PAR2 inhibitor that acting as a negative allosteric regulator on Gα q and Gα 12/13 activity and their downstream effectors. I-287 reduces Complete Freund's adjuvant ( HY-153808 )-induced inflammation in mice and can be used for inflammation/immunology research.

Application

Products | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Lipid Metabolism | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Liver Cancer | Products > Disease Areas > Pain | Products > Disease Areas > Obesity | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Protease Activated Receptor (PAR) | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-148016
• CAS No.: 2014368-93-3
• Molecular Formula: C30H30ClFN4O4
• Molecular Weight: 565.04
• Purity: 99.36%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.42 mM); Clear solution
• Availability: In-stock

Source

Original product source