NW 1028

Overview

NW 1028 is a potent VCP/p97 inhibitor. NW 1028 targets the ND1L domain of p97 and inhibits the degradation of a p97-dependent reporter. NW 1028 has good binding affinity with K d values of 100 and 285 nM for ND1L and full length p97 , respectively. NW 1028 has the function of regulating the mitotic spindle of cells.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > p97

Product Information

• Catalog No.: HY-148122
• CAS No.: 2749599-78-6
• Molecular Formula: C19H21N5O4S
• Molecular Weight: 415.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source