BrP-LPA sodium

Overview

BrP-LPA sodium is a pan-opposite agent for lysophosphatidic acid (LPA). It has antagonistic activity against LPA 1 ( IC 50 = 4520 nM), LPA 2 ( IC 50 = 468 nM), LPA 3 , and LPA 4 . BrP-LPA sodium also has partial agonistic activity for LPA 5 , with its EC 50 being 1282 nM. BrP-LPA sodium has ATX inhibitory activity. BrP-LPA sodium effectively inhibits the migration and invasion of breast cancer cells. BrP-LPA sodium achieves tumor regression and anti-angiogenesis in mice breast cancer xenograft model. BrP-LPA sodium can be used for the study of breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > LPL Receptor | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-148291
• CAS No.: 944265-88-7
• Molecular Formula: C20H39BrNaO6P
• Molecular Weight: 509.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source