SIRT2-IN-11

Overview

SIRT2-IN-11 (AEM1) is a selective SIRT2 inhibitor with an IC 50 value of 18.5 μM. SIRT2-IN-11 p53-dependently induces apoptosis , activates expression of CDKN1A , PUMA and NOXA , and increases acetylation of p53. SIRT2-IN-11 can be used for the research of p53-related cancers.

Application

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Product Information

• Catalog No.: HY-148408
• CAS No.: 1005095-06-6
• Molecular Formula: C21H22N2O
• Molecular Weight: 318.41
• Purity: 99.94%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source