4-Pyridylmethyl adamantanecarboxamide

Overview

4-Pyridylmethyl adamantanecarboxamide (Compound 11) is an Aromatase inhibitor with an IC 50 of 1.5 μM against hAromatase. 4-Pyridylmethyl adamantanecarboxamide inhibits the C17,20-lyase activity of testicular cytochrome P450 17α with an IC 50 of 1600 nM, and also inhibits the 17α-hydroxylase activity of this enzyme with an IC 50 of 7700 nM. 4-Pyridylmethyl adamantanecarboxamide can be used in the research of prostate cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-148430
• CAS No.: 121768-39-6
• Molecular Formula: C17H22N2O
• Molecular Weight: 270.37
• Purity: 99.83%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (9.25 mM); Clear solution
• Availability: In-stock

Source

Original product source