eIF4A3-IN-12

Overview

eIF4A3-IN-12 (compound 62) is a Silvestrol ( HY-13251 ) analogue. eIF4A3-IN-12 interferes the assembling of eIF4F translation complex with EC 50 s of 4, 70 and 5 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-12 can be used for the research of human cancer pathogenesis.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Eukaryotic Initiation Factor (eIF)

Product Information

• Catalog No.: HY-148446
• CAS No.: 1402931-76-3
• Molecular Formula: C27H25ClO7
• Molecular Weight: 496.94
• Purity: 99.98%
• Storage: 4°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Source

Original product source