FGFR-IN-10

Overview

FGFR-IN-10 is an orally active inhibitor of FGFR and Cytochrome P450 ( CYPs ). FGFR-IN-10 inhibits wide type and V564F mutant FGFR2 with IC 50 s of 104.1 nM and 43.6 nM, respectively. FGFR-IN-10 also inhibits CYPs with IC 50 s of 3.33 μM ( CYP2C9 ), 18.75 μM ( CYP2C19 ), 4.34 μM (CYP2CD6), and 0.69 μM ( CYP3A4 ), respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > FGFR | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-148597
• CAS No.: 2847092-41-3
• Molecular Formula: C28H30FN9O2
• Molecular Weight: 543.60
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source