MLKL-IN-5 is a mixed lineage kinase domain-like protein ( MLKL ) inhibitor with a K D of < 10 nM. MLKL-IN-5 exhibits selectivity for RIP3 and RIP1, with K D values of 1-30 μM and > 30 μM, respectively. MLKL-IN-5 mediates necroptosis .
Products | Products > Disease Areas > Others | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Others | Products > Signaling Pathways > Mixed Lineage Kinase | Products > Signaling Pathways > Necroptosis
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