WDR5-0102

Overview

WDR5-0102 is an inhibitor of WDR5 . WDR5-0102 specifically targets the WIN site of WDR5 , disrupts the WDR5-MLL1 interaction, and reduces the histone methyltransferase activity of MLL1. WDR5-0102 exerts dose-dependent toxicity on MDSC -like cells and reduces their osteopontin levels, while showing extremely low cytotoxicity to pancreatic cancer cells. WDR5-0102 can be used in the research of related diseases such as acute myeloid leukemia, lymphoid leukemia, biphenotypic leukemia and pancreatic cancer .

Application

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Product Information

• Catalog No.: HY-148817
• CAS No.: 824960-50-1
• Molecular Formula: C18H19ClN4O3
• Molecular Weight: 374.82
• Purity: 97.07%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 1.67 mg/mL (4.46 mM); Clear solution
• Availability: In-stock

Source

Original product source