MR22

Overview

MR22 is a potent pan- SIK ( salt-inducible kinase ) inhibitor. MR22 no longer exhibits activity on STE group kinases and displays excellent selectivity in a representative kinase panel. MR22-dependent SIK inhibition led to centrosome dissociation and subsequent cell-cycle arrest in ovarian cancer cells.

Application

Products | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > Salt-inducible Kinase (SIK)

Product Information

• Catalog No.: HY-149075
• CAS No.: 3027761-24-3
• Molecular Formula: C18H19F2N5O
• Molecular Weight: 359.37
• Purity: 99.76%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (6.96 mM); Clear solution
• Availability: In-stock

Source

Original product source