KDM5B-IN-4

Overview

KDM5B-IN-4 (compound 11ad) is a lysine demethylase 5B ( KDM5B ) inhibitor with an IC 50 of 0.025 μM KDM5B-IN-4 increases substrate H3K4me1/2/3 level by inhibiting KDM5B in PC-3 cells. KDM5B-IN-4 downregulates PI3K/AKT. KDM5B-IN-4 reduces tumor volume in mice and shows less toxic to organs.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Demethylase

Product Information

• Catalog No.: HY-149091
• CAS No.: 3046228-11-6
• Molecular Formula: C30H30N6O
• Molecular Weight: 490.60
• Purity: 99.68%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 3.33 mg/mL (6.79 mM); Clear solution
• Availability: In-stock

Source

Original product source