RET-IN-22

Overview

RET-IN-22 (compound 17b) is a potent, selective and orally active RET inhibitor with an IC 50 of 20.9 nM and 18.3 nM for wild-type RET and RET-V804M , respectively. RET-IN-22 shows highly selective profile to most kinases, especially to EGFR and VEGFR2. RET-IN-22 has anticancer effects.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > RET

Product Information

• Catalog No.: HY-149099
• CAS No.: 2918281-79-3
• Molecular Formula: C29H31F3N6O4
• Molecular Weight: 584.59
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source