Inosine-5'-diphosphate

Overview

Inosine-5'-diphosphate (IDP) is a decoy substrate of NM23-H2 . Inosine-5'-diphosphate has a superior bond capacity on GDP-binding pocket of NM23-H2 ( K D : 5.0 μM). Inosine-5'-diphosphate abrogates c-MYC transcription, induces apoptosis and G2/M cell cycle arrest by disrupting NM23-H2-Pu27-GQ interactions without affecting NM23-H2-mediated kinase properties. Inosine-5'-diphosphate has antihypoxic, antihyperthermic and antiarrhythmic activity and protects animals against the noxious effects of γ-irradiation. Inosine-5'-diphosphate can be used for cancers like Burkitt's lymphoma and cardiovascular diseases research.

Application

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Product Information

• Catalog No.: HY-149101
• CAS No.: 86-04-4
• Molecular Formula: C10H14N4O11P2
• Molecular Weight: 428.19
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source