Dendrogenin A

Overview

Dendrogenin A (DDA) is a ligand for liver X receptor ( LXR ) , that induces the expression of sodium/iodine symporter, and increases iodine uptake. Dendrogenin A induces cell differentiation of MCF-7, and reactivates the function of lactating cells. Dendrogenin A induces the expressions of the TSH receptor , thyroid peroxidase, and thyroglobulin, and affects thyroid hormone generation. Dendrogenin A exhibits cytotoxicity in cancer cell B-CPAP and 8505c with IC 50 of 4.1 and 6.2 µM. Dendrogenin A arrests the cell cycle at G0/G1 phase.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Vitamin D Related/Nuclear Receptor | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > LXR

Product Information

• Catalog No.: HY-149132
• CAS No.: 1191043-85-2
• Molecular Formula: C32H55N3O2
• Molecular Weight: 513.80
• Purity: 96.7%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source