HPK1-IN-33

Overview

HPK1-IN-33 (compound 21) is a potent Hematopoietic Progenitor Kinase 1 (HPK1) inhibitor with a K i value of 1.7 nM. HPK1-IN-33 inhibits the produce of IL-2 with EC 50 s of 286, >10000 nM in Jurkat WT and Jurkat HPK1 KO cells, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MAP4K

Product Information

• Catalog No.: HY-149206
• CAS No.: 2920000-86-6
• Molecular Formula: C18H16ClFN6
• Molecular Weight: 370.81
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source