CLK1-IN-3

Overview

CLK1-IN-3 (compound 10ad) is a potent and selective Clk1 inhibitor, with an IC 50 of 5 nM and over 300-fold selectivity for Dyrk1A . CLK1-IN-3 also shows a relatively potent inhibition against Clk2 and Clk4 , with IC 50 values of 42 and 108 nM, respectively. CLK1-IN-3 potently induces autophagy in vitro. CLK1-IN-3 can be used for acute liver injury (ALI) research.

Application

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Product Information

• Catalog No.: HY-149262
• CAS No.: 2922550-28-3
• Molecular Formula: C24H23FN6O
• Molecular Weight: 430.48
• Purity: 98.54%
• Storage: 4°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: 2.5 mg/mL (5.81 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source