PKM2/PDK1-IN-1

Overview

PKM2/PDK1-IN-1, one of shikonin thioether derivatives, is a dual inhibitor of PKM2 / PDK1 . PKM2/PDK1-IN-1 inhibits the proliferation of NSCLC cells, and induces apoptosis . PKM2/PDK1-IN-1 induces intercellular ROS production, and regulates the apoptotic proteins, to involves in mitochondrial and death receptor pathway.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > EGFR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Pyruvate Kinase | Products > Signaling Pathways > PDK-1 | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-149275
• CAS No.: 3041957-90-5
• Molecular Formula: C36H43NO7S3
• Molecular Weight: 697.92
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source