Lobeglitazone

Overview

Lobeglitazone is a new type of thiazolidinedione. Lobeglitazone is the orally active agonist for PPAR with EC 50 of 137.4 nM and 546.3 nM for PPARγ and PPARα . Lobeglitazone is the inhibitor for ERK/JNK/Smad/NF-κB signaling pathway. Lobeglitazone exhibits anti-inflammatory, anti-diabetic, anti-fibrotic and anti-atherosclerotic properties.

Application

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Product Information

• Catalog No.: HY-14928
• CAS No.: 607723-33-1
• Molecular Formula: C24H24N4O5S
• Molecular Weight: 480.54
• Purity: 96.18%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.20 mM); Clear solution
• Availability: In-stock

Source

Original product source