ATM Inhibitor-7 is a potent and selective ataxia-telangiectasia mutated ( ATM ) inhibitor with an IC 50 value of 1.0 nM. ATM Inhibitor-7 induces Apoptosis and cell cycle arrest at G2/M phase when combinanted with CPT-11 ( HY-16562 ). ATM Inhibitor-7 combines with CPT-11 shows antitumor activity.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > ATM/ATR | Products > Signaling Pathways > Apoptosis
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