PI3Kα-IN-12

Overview

PI3Kα-IN-12 (compound 13) is a highly selective PI3Kα inhibitor ( IC 50 : 1.2 nM). PI3Kα-IN-12 inhibits HCT-116 and U87-MG with IC 50 s values of 0.83 and 1.25 μM, respectively. PI3Kα-IN-12 (40 mg/kg; IP ) causes tumor regression in a U87-MG cell line xenograft mouse model.

Application

Products | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > PI3K

Product Information

• Catalog No.: HY-149427
• CAS No.: 2966861-50-5
• Molecular Formula: C28H36F2N10O5S3
• Molecular Weight: 726.84
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source