M4K-2009

Overview

M4K2009 is an orally active, blood-brain barrier permeable type I ALK2 inhibitor, with an IC 50 value of 8-13 nM against human ALK2 . M4K2009 exhibits moderate off-target inhibitory activity against hERG potassium channels ( Potassium Channel ), with an IC 50 of 8 μM against the human channel. M4K2009 can be used in studies related to diffuse intrinsic pontine glioma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Glioma | Products > Disease Areas > CNS Neoplasm | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-β Receptor | Products > Signaling Pathways > Potassium Channel

Product Information

• Catalog No.: HY-149591
• CAS No.: 2600795-07-9
• Molecular Formula: C25H29N3O3
• Molecular Weight: 419.52
• Purity: 99.35%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.96 mM); Clear solution
• Availability: In-stock

Source

Original product source