BMS-684

Overview

BMS-684 is a selective DGKα inhibitor with an IC 50 of 15 nM. BMS-684 inhibits DGKα kinase activity with >100-fold selectivity over the related DGK type I family members DGKβ and DGKγ. BMS-684 does not inhibit any of the other seven DGK isozymes.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DGK

Product Information

• Catalog No.: HY-149665
• CAS No.: 313552-29-3
• Molecular Formula: C27H26N4O3
• Molecular Weight: 454.52
• Purity: 98.52%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: 1.43 mg/mL (3.15 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source