BMS-332

Overview

BMS-332 is a dual DGKα/ζ lipid kinase inhibitor, with IC 50 s of 5 and 1 nM against DGKα and DGKζ , respectively. BMS-332 enhances the antigen-specific T cell response. BMS-332 reduces the viral load in the liver and spleen when combined with anti-PD-1 in chronic infection models. BMS-332 can be used for the study of T cell immune checkpoint strategy.

Application

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Product Information

• Catalog No.: HY-149667
• CAS No.: 2407892-15-1
• Molecular Formula: C29H27F2N5O
• Molecular Weight: 499.55
• Purity: 99.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.43 mg/mL (2.86 mM); Clear solution
• Availability: In-stock

Source

Original product source