EZH2-IN-17

Overview

EZH2-IN-17 (compound 28) is a potent and orally active EZH2 inhibitor with an IC 50 value of 0.95 nM. EZH2-IN-17 exhibits high anti-proliferation activity against different lymphoma cell lines including WSU-DLCL2, Pfeiffer and Karpas-422 (IC50 values of 2.36 nM, 1.73 nM, and 1.82 nM, respectively).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Methyltransferase

Product Information

• Catalog No.: HY-149726
• CAS No.: 2489672-09-3
• Molecular Formula: C36H46N4O4
• Molecular Weight: 598.77
• Purity: 99.35%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Solubility: ≥ 2.5 mg/mL (4.18 mM); Clear solution
• Availability: In-stock

Source

Original product source