SHP2-IN-23

Overview

SHP2-IN-23 (compound 30) is an orally active SHP2 inhibitor (IC 50 =38 nM) with excellent in vivo efficacy and pharmacokinetic profiles. SHP2-IN-23 inhibits ERK phosphorylation with IC 50 =5 nM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2 | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-149759
• CAS No.: 2415989-91-0
• Molecular Formula: C24H23ClN8S
• Molecular Weight: 491.01
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source