ML786 dihydrochloride

Overview

ML786 dihydrochloride is a potent and orally bioavailable Raf inhibitor, with IC 50 s of 2.1, 4.2, and 2.5 nM for V600E ΔB-Raf , wt B-Raf , and C-Raf , respectively. ML786 dihydrochloride also inhibits Abl-1 , DDR2 , EPHA2 , KDR , and RET ( IC 50 =<0.5, 7.0, 11, 6.2, 0.8 nM). ML786 dihydrochloride can be used for the research of cancers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Raf | Products > Signaling Pathways > Bcr-Abl | Products > Signaling Pathways > Discoidin Domain Receptor | Products > Signaling Pathways > VEGFR | Products > Signaling Pathways > RET | Products > Signaling Pathways > Ephrin Receptor

Product Information

• Catalog No.: HY-14979A
• CAS No.: 1237536-18-3
• Molecular Formula: C29H31Cl2F3N4O3
• Molecular Weight: 611.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source