SIQ17 is an EGFR inhibitor that inhibits its activity by occupying the ATP-binding site, with IC 50 of 0.62 nM. SIQ17 shows more effective EGFR-TK inhibitory activity compared to the known inhibitor Erlotinib ( HY-50896 ) ( IC 50 of ∼20 nM). SIQ17 can be used for cancer research
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