Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor (IC 50 : 17.01 nM). Pim-1 kinase inhibitor 4 also has antioxidant activity and inhibits DPPH. Pim-1 kinase inhibitor 4 induces apoptosis in PC-3 cell, and inhibits PC-3 cell growth with an IC 50 of 16 nM. Pim-1 kinase inhibitor 4 can be used for research of prostate cancer .
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