RMC-4745

Overview

RMC-4745 is a selective dual-site inhibitor of mTORC1 , with a selectivity of 35 times for mTORC1 and mTORC2 . RMC-4745 inhibits the proliferation of MCF-7 cells and upregulates Caspase-3/7 activity to induce cell apoptosis . RMC-4745 does not cause the upregulation of HER3 due to the inhibition of mTORC2 . RMC-4745 can be used for the study of breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > mTOR | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Caspase

Product Information

• Catalog No.: HY-150108
• CAS No.: 2250059-80-2
• Molecular Formula: C94H142N12O24
• Molecular Weight: 1824.20
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source