Diclofenac

Diclofenac
  • CAS No.:15307-86-5
  • Grade:99.92%
  • Formula:C14H11Cl2NO2
  • M.W.:296.15
  • Solvent:≥ 2.08 mg/mL (7.02 mM); Clear solution

Overview

Diclofenac is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC 50 s of 4 and 1.3 nM for human COX-1 and COX-2 in CHO cells, and 5.1 and 0.84 μM for ovine COX-1 and COX-2 , respectively. Diclofenac induces apoptosis of neural stem cells (NSCs) via the activation of the caspase cascade.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Arthritis | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Prostate Cancer | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Pancreatic Cancer | Products > Disease Areas > Depression | Products > Disease Areas > Digestive System Inflammation | Products > Disease Areas > Rheumatoid Arthritis | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Digestive System Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > COX | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-15036
  • CAS No.: 15307-86-5
  • Molecular Formula: C14H11Cl2NO2
  • Molecular Weight: 296.15
  • Purity: 99.92%
  • Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
  • Solubility: ≥ 2.08 mg/mL (7.02 mM); Clear solution
  • Availability: In-stock

Source

Original product source


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