HDAC-IN-45 (Compound 14) is a small molecule HDAC inhibitor and has anticancer activity, also can forms a hydrogen bond with residue Y303. HDAC-IN-45 (Compound 14) has substantial inhibitory effects towards HDAC1 , 2 and 3 isoforms with IC 50 values of 0.108, 0.585 and 0.563 μM respectively.
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