PARP1/BRD4-IN-2

Overview

PARP1/BRD4-IN-2 is a potent and selective PARP1 and BRD4 inhibitor with IC 50 values of 197 nM and 238 nM, respectively. PARP1/BRD4-IN-2 inhibits DNA damage repair, arrests G0/G1 transition and induces apoptosis . PARP1/BRD4-IN-2 has anti-tumor activity in MDA-MB-468 xenograft mouse model. PARP1/BRD4-IN-2 can be used for researching triple-negative breast cancer (TNBC).

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-150613
• CAS No.: 3037993-97-5
• Molecular Formula: C25H20N4O4
• Molecular Weight: 440.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source