S07-2010

Overview

S07-2010 is a potent pan- AKR1C (aldo-keto reductase family 1 member C) inhibitor, with IC 50 values of 0.19, 0.36, 0.47, and 0.73 μM for AKR1C3 , AKR1C4 , AKR1C1 and AKR1C2 , respectively. S07-2010 induces apoptosis in A549/DDP cells. S07-2010 strengthens the cytotoxicity of chemotherapeutic agents in drug-resistant cells. S07-2010 significantly inhibits the proliferation of drug-resistant cells.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Lung Cancer | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Drug Resistance

Product Information

• Catalog No.: HY-150644
• CAS No.: 1223194-71-5
• Molecular Formula: C19H21N3O3S
• Molecular Weight: 371.45
• Purity: 98.35%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.08 mg/mL (5.60 mM); Clear solution
• Availability: In-stock

Source

Original product source