BMS-1233

Overview

BMS-1233 is an orally active inhibitor for programmed cell death-ligand 1 ( PD-L1 ), with IC 50 of 14.5 nM. BMS-1233 promotes cell death of HepG2 in a Jurkat T cell and HepG2 cell co-culture model, exhibits antitumor activity against melanoma in mouse model.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > PD-1/PD-L1

Product Information

• Catalog No.: HY-151066
• CAS No.: 2447065-99-6
• Molecular Formula: C35H33ClN2O4
• Molecular Weight: 581.10
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source