Y-29794

Overview

Y-29794 is a selective, orally active inhibitor for non-peptide prolyl endopeptidase ( PREP ), with an IC 50 of 3 nM and a K i of 0.95 nM. Y-29794 enhances the effect of thyrotropin-releasing hormone ( TRH ) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 exhibits anticancer activity through inhibition of the IRS1-AKT-mTORC1 pathway. Y-29794 penetrates the brain-blood barrier (BBB).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Prolyl Endopeptidase (PREP)

Product Information

• Catalog No.: HY-15113
• CAS No.: 129184-48-1
• Molecular Formula: C23H34N2OS2
• Molecular Weight: 418.66
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source