Y-29794 tosylate

Overview

Y-29794 tosylate is a selective, orally active inhibitor for non-peptide prolyl endopeptidase ( PREP ), with an IC 50 of 3 nM and a K i of 0.95 nM. Y-29794 tosylate enhances the effect of thyrotropin-releasing hormone ( TRH ) on the release of ACh in the rat hippocampus, exhibits potential neuroprotective efficacy. Y-29794 tosylate exhibits anticancer activity through inhibition of the IRS1-AKT-mTORC1 pathway. Y-29794 tosylate penetrates the brain-blood barrier (BBB).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Prolyl Endopeptidase (PREP)

Product Information

• Catalog No.: HY-15113A
• CAS No.: 143984-17-2
• Molecular Formula: C30H42N2O4S3
• Molecular Weight: 590.86
• Purity: 99.86%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source