DHFR-IN-4

Overview

DHFR-IN-4 is a potent dihydrofolate reductase ( DHFR ) inhibitor with an IC 50 value of 123 nM. DHFR-IN-4 also has inhibitory activity against EGFR and HER2 with IC 50 s of 246 nM and 357 nM, respectively. DHFR-IN-4 has remarkable broad spectrum cytotoxic potency against cancer cells.

Application

Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > JAK/STAT Signaling | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Dihydrofolate reductase (DHFR) | Products > Signaling Pathways > EGFR

Product Information

• Catalog No.: HY-151159
• CAS No.: 2820126-49-4
• Molecular Formula: C18H21N5O2S
• Molecular Weight: 371.46
• Purity: 99.19%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source