NCATS-SM1441 (compound 52) is a lactate dehydrogenase ( LDH ) inhibitor ( IC 50 =40 nM). By inhibiting the activity of LDH , NCATS-SM1441 is able to reduce the production of lactic acid in cancer cells, helping to slow or stop the proliferation of cancer cells. NCATS-SM1441 can be used to study cancer metabolism.
Products | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Lactate Dehydrogenase
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